Detall de la convocatòria

Característiques

Característica
Objectiu de la convocatòria
The awards aim to fund cutting-edge research projects that focus on understanding the underlying mechanism of disease, addressing lupus heterogeneity, and identifying novel biomarkers.
Característiques principals
Examples of pertinent topics include, but are not limited to:
  • Mechanism of disease: Mining of bulk and single-cell transcriptomic and proteomic datasets derived from lupus patient blood and target tissues (e.g., skin, joint, kidney);
  • Target discovery and validation: Characterization of genetic drivers of lupus, such as but not limited to understanding gain-of-function or loss-of-function risk alleles, eQTLS, or mRNA splicing;
  • Biomarker identification: Identify or validate early biomarkers of clinical flares, remission or response to therapy;
  • Patient selection: Novel methods of identifying SLE patient subsets based on immunological and clinical heterogeneity;
  • Clinical endpoint derivation and harmonization: addressing the need for outcome measures for skin disease, lupus-specific arthritis measures, and other endpoints that would facilitate and accelerate the conduct of clinical trials in lupus and its complications.
    • Lloc de presentació
    El personal de l'IMIM i PSMAR que necessiteu més informació adreceu-vos a:
    Servei de Recerca. C/ Doctor Aiguader, 88. 08003-Barcelona. Tel.: 93.316.05.76.
    Marta López: mlopez4@imim.es Ext.: 1576
    Carol Barnwell: cbarnwell@imim.es Ext.: 1670
    Convocatòria (URL)
    Call:
    https://www.lupusresearch.org/research-and-clinical-trials/research/funding-opportunities/
    Informació addicional
    A two-stage application process will be employed. A 2-page Letter of Intent (LOI) will be used to judge the significance, novelty, and alignment of the proposed project concept with the LRA-Celgene Accelerator Award. LOIs must be submitted electronically via proposalCENTRAL.com by 11:59 pm ET on October 25, 2019. Only applicants whose LOIs have successfully passed this first review stage will be invited to submit full applications.
    https://proposalcentral.altum.com
    Instructions and application forms should be downloaded from the proposal CENTRAL.
    Requisits
    Individuals with a doctoral degree (MD, PhD, DO, or equivalent), holding a faculty, or equivalent, position and leading an independent research team at an academic, nonprofit, or government research institution are eligible to apply. The Lupus Research Alliance does not impose geographic restriction on its applicants, and researchers working outside of the United States are encouraged to apply.
    Dotació
    Up to $150,000 per year (for a maximum of two years - total amount up to $300,000).
    Durada
    Maximum 2 years.

    Arxius

    Arxiu
    LRA-Celgene-RFA-2019_Final.pdf