Detall de la convocatòria

Característiques

Característica
Objectiu de la convocatòria
Grants to advance our understanding of the genetic basis of ASD and the molecular and cellular consequences of genetic risk, and to provide a foundation for the development of treatments for select genetically defined forms of the condition.
Característiques principals
Over the past decade, the scientific community has identified more than 100 highly penetrant risk genes for ASD, owing in part to analyses of SFARI-sponsored cohorts such as SPARK (Simons Foundation Powering Autism Research for Knowledge), Simons Searchlight and Simons Simplex Collection (SSC). Although these genetic findings have allowed for a better understanding of the biological underpinnings of ASD, much remains to be done to elucidate the complexity of ASD genomics and to use this knowledge to develop new genetic therapies.
In this RFA, we seek proposals in three broad areas of ASD genomics:
(1) risk gene discovery and systems biology,
(2) functional analysis of variants associated with ASD risk genes and
(3) gene-targeted therapies. Successful proposals with a focus on the first two areas will likely involve large-scale analyses.
Lloc de presentació
El personal de l'IMIM i PSMAR que necessiteu més informació adreceu-vos a:
Servei de Recerca. C/ Doctor Aiguader, 88. 08003 Barcelona. Tel.: 93.316.04.00.
• Carol Barnwell, cbarnwell@imim.es. Ext.: 1670
• Marta López, mlopez4@imim.es Ext.: 1576
Convocatòria (URL)
https://www.sfari.org/grant/2021-genomics-of-asd-pathways-to-genetic-therapies-request-for-applications/
Impresos (URL)
https://proposalcentral.altum.com/
Informació addicional
Informational Sessions for Potential Applicants:
To answer questions about this RFA, SFARI will hold an informational Zoom meeting on May 20, 2021 at 1:00 p.m. ET. Interested applicants can register at: https://www.sfari.org/event/sfari-2021-genomics-of-asd-pathways-to-genetic-therapies-rfa-informational-session
Requisits
  • All applicants and key collaborators must hold a Ph.D., M.D. or equivalent degree and have a faculty position or the equivalent at a college, university, medical school or other research facility.
  • Principal investigators (PIs) who do not have substantial ASD clinical expertise should include a close collaborator with such expertise on their grant application.
  • SFARI recognizes the importance of diverse viewpoints for scientific advancement. As such, SFARI strongly encourages the inclusion of researchers who span institutions, career stages and groups historically underrepresented in science.
  • Applications may be submitted by domestic and foreign nonprofit organizations; public and private institutions, such as colleges, universities, hospitals, laboratories, and units of state and local government; and eligible agencies of the federal government. There are no citizenship or country requirements.
    • Dotació
    Annual budget between $200,000 and $400,000
    Durada
    2 to 3 years

    Arxius

    Arxiu