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Objectiu de la convocatòria
Funding for pre-clinical, translational, and early clinical research with the potential to produce unusually high impact, near-term advancements in melanoma prevention, detection, diagnosis, staging, and treatment.
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Característiques principals
For the 2021-2022 cycle, MRA seeks proposals in the following areas, which are focused on current unmet clinical needs in melanoma. These areas are of particular interest, will receive special consideration, and can include pre-clinical, translational, clinical, and/or correlative studies:
Uncovering novel and/or refining existing strategies to improve prevention and early detection;
Identifying prognostic biomarkers of high-risk disease/precursor lesions;
Developing strategies to prevent and/or treat metastatic disease, including neoadjuvant/ adjuvant therapies, and treatment for brain metastases and leptomeningeal disease;
Advancing non-T cell-based immunotherapy approaches (i.e., NK cells, macrophages, etc.);
Developing treatment strategies for difficult-to-treat melanoma subtypes such as acral, mucosal, or uveal melanoma, pediatric/adolescent, and/or BRAF wildtype, NRAS or NF1 mutant genotypes; and
Identifying strategies to overcome primary and secondary treatment resistance.
Types of awards:
Young Investigator Award: Scientists within five years of their first academic faculty appointment. A mentorship commitment from a senior investigator is required.
Team Science Award: Multidisciplinary team that consists of two or more established Principal Investigators, one of whom is designated the Administrative PI, a Young Investigator with complementary expertise, and a Mentor for the Young Investigator.
Team Science Academic-Industry Partnership Award: To facilitate interactions between the academic and industrial research sectors. These awards will be co-funded by MRA and an industry partner whose involvement is essential to the project.
Pilot Award: Senior investigators who propose potentially transformative ideas that do not have extensive preliminary data but articulate a clear hypothesis and translational goals
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Lloc de presentació
El personal de l'IMIM i PSMAR que necessiteu més informació adreceu-vos a:
Servei de Recerca. C/ Doctor Aiguader, 88. 08003 Barcelona. Tel.: 93.316.04.00.
• Carol Barnwell, cbarnwell@imim.es. Ext.: 1670
• Marta López, mlopez4@imim.es Ext.: 1576
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Convocatòria (URL)
https://www.curemelanoma.org/research/request-for-proposals/mra-general-rfp/
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Requisits
General eligibility requirements:
Principal Investigators (PIs) must hold a full-time faculty appointment at the level of Assistant Professor (or equivalent) or above at an academic or other non-profit research institution within or outside the United States.
PIs must be able to show clear evidence of an independent research program.
If previously funded by MRA, applicant must be up-to-date on all reporting requirements.
Fellows or those in other training or research support positions are not eligible to apply.
Individuals employed by state or federal government agencies may participate in research proposals as non-funded collaborators, but may not apply for MRA funding.
Investigators need not be specifically trained in melanoma research; however, they should be working in an environment capable of conducting high-quality, high-impact melanoma research.
An investigator may serve as PI on only one proposal submitted to MRA for any of the award mechanisms in this cycle. This includes any Special Opportunity Awards.
Mentors for Young Investigator Award applicants may serve as a PI on a separate proposal this cycle; however, that proposal must represent a distinct hypothesis from the Young Investigator’s proposal.
Multiple applications will be accepted from a single institution, provided that each application has a different PI and represents a distinct hypothesis.
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Dotació
Young Investigator Award: $85,000 per year for 3 years
Team Science Award: Up to $300,000 per year for three years
Team Science Academic-Industry Partnership Award: Up to $300,000 per year for three years. Industrial partner must provide funds or in-kind support
Pilot Award: $50,000 per year for 2 years
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Durada
Young Investigator Award: 3 years
Team Science Award: 3 years
Team Science Academic-Industry Partnership Award: 3 years
Pilot Award: 2 years
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Documentació
Applicants must utilize the proposalCENTRAL online application tool at https://proposalcentral.com/
A detailed list of the documents to provide is given in the RFP document.
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AVÍS IMPORTANT
Please note that each instrument has different deadlines:
October 6: Team Science Award Letters of Intent Due
November 3: Young Investigator Award Eligibility Checklist Due
November 17: Young Investigator and Pilot Awards Full Proposals Due
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