Detall de la convocatòria

Característiques

Característica
Objectiu de la convocatòria
Research projects on the application of single-cell biology methods to rare inflammatory pediatric diseases that will clarify cellular mechanisms of disease, understand disease heterogeneity, and improve biomarker identification or diagnostics, performed by collaborative teams bringing together patient-led rare disease organizations and research teams.
Característiques principals
The overarching goal is to support interdisciplinary teams as they characterize the cellular mechanisms underlying rare inflammatory diseases, including possible identification of biomarkers and elucidation of disease pathways that will clarify disease stratification or identify therapeutic opportunities. Patient organizations are expected to be active collaborators on this research opportunity and full partners in the development of the grant application to directly inform research questions that will have the greatest impact on rare disease patients, and to engage in study design, patient engagement, and research dissemination.
Team composition: Collaboration is a central feature of this RFA and grant program. Applications will each have two lead Principal Investigators (PIs): one representing the research team and the other representing the patient organization. Teams should be made up of a minimum of two investigators with a maximum of five investigators, including the patient organization leader. Applications should be co-written by the researchers and the patient-organization representative. Applications will be accepted from newly formed collaborative teams who have not worked together previously or established researcher-patient organization collaborative teams who are proposing new research directions. We will prioritize teams that are taking a fresh, innovative approach to tackling these challenging diseases.
Lloc de presentació
El personal de l'IMIM i PSMAR que necessiteu més informació adreceu-vos a:
Servei de Recerca. C/ Doctor Aiguader, 88. 08003 Barcelona. Tel.: 93.316.04.00.
• Carol Barnwell, cbarnwell@imim.es. Ext.: 1670
• Marta López, mlopez4@imim.es Ext.: 1576
Convocatòria (URL)
https://chanzuckerberg.com/rfa/patient-partnered-collaborations-ppc-for-single-cell-analysis-of-rare-inflammatory-pediatric-disease/
Requisits
  • Each Coordinating PI and patient organization may only submit one application to this RFA.
  • Each application should designate one Principal Investigator (PI) as the Coordinating Principal Investigator (Coordinating PI). Note that institutions outside the U.S. may not subcontract to U.S. institutions, so please be mindful when selecting the Coordinating PI/institution.
  • PIs/co-PIs must have an academic appointment and be in an independent faculty position or equivalent at an accredited college, university, medical school, or other research facility at the time of grant start. Independence is demonstrated by institutional support for independent research activities.
  • Collaborators from companies are permitted as long as no funds are requested to support them or their work and there is full compliance with CZI policies regarding open science.
  • Early-career investigators are strongly encouraged to apply as Coordinating PIs as well as co-PIs.
  • Patient organizations must be patient-led rare disease organizations

    Please check the guidelines for complete eligibility requirements.
    • Dotació
    $2,000,000
    Durada
    4 years

    Arxius

    Arxiu
    Instructions-Patient-Partnered-Collaborations-for-Single-Cell-Analysis-of-Rare-Inflammatory-Pediatric-Disease.pdf
    CZI-PPC-for-Single-Cell-Analysis-of-Rare-Disease-RFA-Packet.pdf